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Acabrunat Capsule

100mg

Salt Composition

Acalabrutinib

Marketed By

Natco Pharma Ltd.

Country of Origin

India

9,450.00

MRP:

15,500.00

Inclusive of all taxes

Product Overview:

Acabrunat 100mg Capsule contains Acalabrutinib, a targeted anticancer therapy primarily used in treating specific blood cancers such as Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukemia (CLL).

Mechanism of Action:

Acalabrutinib is a Bruton’s tyrosine kinase (BTK) inhibitor. It blocks BTK enzyme activity, which plays a key role in B-cell receptor signaling, thus preventing the growth and spread of malignant B-cells.

Uses:  

  • Mantle Cell Lymphoma (MCL)  
  • Chronic Lymphocytic Leukemia (CLL)  
  • Small Lymphocytic Lymphoma (SLL)

 

Common Side Effects:  

  • Headache  
  • Diarrhea  
  • Fatigue  
  • Low platelet count  
  • Muscle pain  
  • Infections (especially respiratory)

 

Drug Interactions:  

  • Avoid concurrent use with strong CYP3A inhibitors or inducers (e.g., ketoconazole, rifampicin)  
  • Use with caution if patient is on anticoagulants or antiplatelet drugs  
  • May interact with proton pump inhibitors (PPIs)

 

Caution With:  

  • Patients with a history of bleeding disorders  
  • Liver or kidney impairment  
  • Those receiving other cancer therapies concurrently

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